The Innovation Discovery Grants (IDG) program provides non-dilutive funding for commercialization work that is not supported by traditional research sponsors.
Innovation Discovery Grants past winners
A Novel Convection Enhanced Delivery System for Brain Malignancies
Miles Cunningham, MD, PhD
McLean Hospital
FastLine: Single-Handed Venous Access Device
Hilary Gallin, MD, MBA
Massachusetts General Hospital
Graham Lieberman, MD, MBA
Massachusetts General Hospital
Development of KRAS Degraders in Cancer
Vidyasagar Koduri, MD, PhD
Brigham and Women’s Hospital
Restoring Tumor Immunogenicity in Glioblastoma Multiforme (GBM)
Choi-Fong Cho, PhD
Brigham and Women’s Hospital
Developing First-in-Class mRNA Methyltransferase Inhibitor
Li Lan, MD, PhD
Massachusetts General Hospital
Auditory Mirror Therapy for Tinnitus
Clas Linnman, PhD
Spaulding Rehabilitation
Noninvasive Diagnosis of Middle-Ear Pathologies with Machine Learning
Hamid Motallebzadeh, PhD
Mass Eye and Ear
Small-Molecule MMP Inhibitors for Allergic Inflammation
Jin Mo Park, PhD
Massachusetts General Hospital
Neutralizing Antibody to FSTL3 as an Immunotherapy in Ovarian Cancer
David Pepin, PhD
Massachusetts General Hospital
Circulating Microparticle Proteins Predict Pregnancies Complicated by Placenta Accreta Spectrum
Hope Yu, MD
Brigham and Women’s Hospital
Generating Superior 'Killers' for Adoptive Cell Therapy in Cancer
Lydia Lynch, PhD
Brigham and Women's Hospital
Novel Strategies to Enhance Tfr Treatment of Autoimmunity
Peter Sage, PhD
Brigham and Women's Hospital
Long-Lasting mRNA Therapy for Genetic Disorders
Jinjun Shi, PhD
Brigham and Women's Hospital
AAV-Based Gene Replacement Therapy Improves Targeting and Clinical Outcomes in a Childhood CNS Disorder
Yulia Grishchuk, PhD
Mass Eye and Ear
Towards a Permanent Genetic Cure for Spinal Muscular Atrophy
Benjamin Kleinstiver, PhD
Massachusetts General Hospital
Differentiation of Retinal Neurons for Cell Replacement in Glaucoma
Petr Baranov, MD, PhD
Mass Eye and Ear
Brain Penetrant AAV Vectors for CNS Gene Therapy
Fengfeng Bei, PhD
Brigham and Women’s Hospital
Commensal Papillomavirus Vaccine Development for Skin Cancer Therapy
Shawn Demehri, MD, PhD
Massachusetts General Hospital
Harnessing Neutrophil Plasticity for the Treatment of Cancer
Tanya Mayadas, PhD
Brigham and Women's Hospital
A Clinically Applicable AI Toolbox for Dystonia Diagnosis
Kristina Simonyan, MD, PhD
Mass Eye and Ear
Down Syndrome Clinic to You (DSC2U)
Brian Skotko, MD
Massachusetts General Hospital
Addressing the Need for Early, Accurate Diagnosis of Parkinson’s Disease: A New PET Radiotracer
Anna Sromek, PhD
McLean Hospital
Computational and experimental deconvolution of circulating exosomal signals in melanoma immunotherapy patients
Genevieve Boland, MD, PhD
Massachusetts General Hospital
Embryo assessment and selection using artificial intelligence
Charles Bormann, PhD
Massachusetts General Hospital
A generalizable artificial intelligence platform for brain cancer frozen section diagnosis
Jeffrey Golden, MD
Brigham and Women's Hospital
Making the 'invisible' visible: bringing intimate partner violence into focus
Bharti Khurana, MD
Brigham and Women's Hospital
Developing a novel machine learning algorithm to automate drug infusions in the operating room and ICU
Vesela Kovacheva, MD, PhD
Brigham and Women's Hospital
Artificial Intelligence Diffraction Analysis (AIDA)
Hakho Lee, PhD
Massachusetts General Hospital
Virtual biopsy of brain injury: deep learning to identify diagnostic metabolic biomarkers
Alexander Lin, PhD
Brigham and Women's Hospital
Automatic cerebral lesion detection and disease progression in patients with Adrenoleukodystrophy (ALD)
Patricia Musolino, MD, PhD
Massachusetts General Hospital
Disease-specific testing of an artificial intelligence system for tight blood pressure control
Andrew Reisner, MD
Massachusetts General Hospital
Live pilot test of an artificial intelligence system for trauma care decision-support
Andrew Reisner, MD
Massachusetts General Hospital
Finding needles in the haystack, using machine learning and natural language processing to identify patients and track disease progression
Li Zhou, MD, PhD
Brigham and Women's Hospital
Using deep learning to predict next-day patient discharges to optimize hospital capacity management
Peter Dunn, MD
Massachusetts General Hospital
A web-based neural network calculator for ovarian cancer screening using serum miRNA
Kevin Elias, MD
Brigham and Women's Hospital
Machine learning for optimized intraoperative multiplexed quantitative optical image guidance for brain tumor surgery
Alexandra Golby, MD
Brigham and Women's Hospital
DeepROP - a point-of-care system for diagnosis of plus disease in retinopathy of prematurity
Jayashree Kalpathy-Cramer, PhD
Massachusetts General Hospital
Breast cancer scanning initiative: predicting unnecessary surgeries in high-risk-breast lesions
Jochen Lennerz, MD, PhD
Massachusetts General Hospital
Ultrasound-based sensors for physiological monitoring and how they can make MRI and PET/CT scanners work better
Bruno Madore, PhD
Brigham and Women's Hospital
Augmented digital microscopy for diagnosis of endometrial neoplasia
George Mutter, MD
Brigham and Women's Hospital
Deep-learning facilitated lesion detection in medical images
Jinsong Ouyang, PhD
Massachusetts General Hospital
Poly-exposure risk scores for psychiatric disorders
Martin Teicher, MD, PhD
McLean Hospital
Development of a machine learning algorithm-guided approach to treatment selection for depressed patients
Christian Webb, PhD
McLean Hospital
Artificial intelligence-based seizure detection and classification
Brandon Westover, MD, PhD
Massachusetts General Hospital
The identification of intracranial hemorrhage using machine-learning analysis of sparse transcranial ultrasound signal
Philip White, PhD
Brigham and Women's Hospital
Scar-free fractional microbiopsy
W. Gerald (Jay) Austen, MD
Massachusetts General Hospital
Therapeutic microbiota in food allergy
Lynn Bry, MD, PhD
Brigham and Women's Hospital
A noninvasive optical monitoring device system for diagnosis & quantitative monitoring of peripheral artery dysfunction
Blaise Frederick, PhD
McLean Hospital
Long-acting oxytocin formulation for treatment of obesity
Elizabeth Lawson, MD
Massachusetts General Hospital
Gene therapy platform for the treatment of inherited deafness
Casey Maguire, PhD
Massachusetts General Hospital
Development of long-acting PTH analogs for treatment of hypoparathyroidism
Michael Mannstadt, MD
Massachusetts General Hospital
Granulocyte progenitor transfusions for the treatment of patients with neutropenia
Michael Mansour, MD, PhD
Massachusetts General Hospital
EveryBaby: wireless heart rate sensor for feedback during newborn resuscitation
Kristian Olson, MD
Massachusetts General Hospital
SMOC2: a novel therapeutic target for kidney fibrosis
Vishal Vaidya, PhD
Brigham and Women's Hospital
Anti-LAP antibody: a new checkpoint inhibitor for the treatment of cancer
Howard Weiner, MD
Brigham and Women's Hospital
Treatment of vein graft disease by suppressing Dll4-notch signaling
Masanori Aikawa, MD, PhD
Brigham and Women's Hospital
Novel approach for prevention of vein graft intimal hyperplasia
W. Gerald (Jay) Austen, MD
Massachusetts General Hospital
Knee range of motion monitoring device
Paolo Bonato, PhD
Spaulding Rehabilitation Hospital
Novel treatment for kidney diseases
Joseph Bonventre, MD, PhD
Brigham and Women's Hospital
Novel non-invasive markers of early inflammation in the kidney
Sylvie Breton, PhD
Massachusetts General Hospital
Noninvasive imaging of fibrinogenesis
Peter Caravan, PhD
Massachusetts General Hospital
Treatment for ovarian cancer
Patricia K. Donahoe, MD
Massachusetts General Hospital
Reducing healthcare utilization in pulmonary embolism
Raul San Jose Estepar, PhD
Brigham and Women's Hospital
Treatment of liver disease with a GLP-a fragment
Joel Habener, MD
Massachusetts General Hospital
Targeting the gut to prevent the metabolic syndrome
Richard Hodin, MD
Massachusetts General Hospital
Rapid diagnostic for infectious diseases
Deborah Tan Hung, MD, PhD
Massachusetts General Hospital
Fogarty style balloon-tipped epidural catheter
Ronald Hurley, MD
Brigham and Women's Hospital
IDG portable magnetic resonance device for the pulmonary ICU\
Samuel Patz, PhD
Brigham and Women's Hospital
High throughput sequencing to identify novel vaccine antigens
Gerald Pier, PhD
Brigham and Women's Hospital
Sensors for pediatric anesthetic monitoring
Patrick Lee Purdon, PhD
Massachusetts General Hospital
A device for low field magnetic stimulation
Michael Rohan, PhD
McLean Hospital
Highly accurate freehand volumetric ultrasound device
Anthony Samir, MD
Massachusetts General Hospital
Nonsurgical alternatives to gastric bypass for treatment of type 2 diabetes
Ali Tavakkoli, MD, MBBS
Brigham and Women's Hospital
Development of hemopexin as prophylaxis for hem-related pathology in premature infants
H. Shaw Warren, MD
Massachusetts General Hospital
New generation micro dissection for rapid molecular testing
Yukako Yagi, PhD
Massachusetts General Hospital