Glaucoma is the second leading cause of blindness in the world. People can go years without detecting the condition; they typically experience symptoms only when vision loss becomes permanent.
According to David S. Friedman, MD, PhD, MPH, a Mass General Brigham glaucoma specialist, about 90% of people in developing countries are unaware they have the disease. Even in the United States, about half of people with glaucoma don’t know they have it.
“We have come a long way in our ability to diagnose and treat glaucoma from when I first began practicing medicine,” says Dr. Friedman. “But much work needs to be done, especially when it comes to catching the condition sooner.”
Dr. Friedman serves as director of the Glaucoma Service at Mass Eye and Ear. He explains how patients can identify glaucoma signs and symptoms and what treatments can stop or prevent further damage.
The optic nerve connects the eye to the brain. If the nerve is damaged, the message from the eye is not recognized. Glaucoma, a form of damage to the optic nerve, can lead to vision loss, or blindness, if left untreated.
While glaucoma can develop at any age, it is much more common in older adults. Those at an increased risk of glaucoma include people who:
Race and ethnicity elevate risk, too. African Americans and Hispanic Americans are much more likely to develop glaucoma than white people.
Patients rarely notice glaucoma signs and symptoms until it is too late. No current treatments can reverse damage from the condition, let alone vision loss.
Two main types of glaucoma exist:
Primary open-angle glaucoma is the most common type of glaucoma.
The condition develops slowly, and few obvious symptoms occur at its earliest stages. While experts are unsure of what causes this type of glaucoma, they suspect eye pressure plays a role. Too much pressure presses liquid inside the eye against the optic nerve, damaging it.
Early symptoms include:
Clouded vision
Difficulty seeing when lighting conditions change or in low-light situations
In later stages of the disease, patients may experience:
Loss of side vision
Damage to central vision
The blue or brown ring of the eye, known as the iris, controls how much light enters the eye. The iris can sometimes block fluid draining from the eye. When this happens, angle-closure glaucoma occurs.
While most people with angle-closure glaucoma do not experience symptoms, some can experience sudden spikes in eye pressure.
A sudden spike in eye pressure can lead to acute and permanent vision loss. This is considered a medical emergency. Symptoms and signs may include:
Eye pain
Seeing halos around lights
Dilated pupils
Red eyes
Nausea and vomiting
A thorough eye exam helps diagnose glaucoma. Eye exams can assess damage to the optic nerve, even during early stages of the condition. If a doctor suspects damage, they will order additional tests. These include a visual field test to examine side vision. The test can identify vision loss a patient might not know about.
“While many people might just think of high eye pressure when they think of glaucoma, about half of all glaucoma cases occur in eyes with pressure in the normal range,” says Dr. Friedman. “That’s why checking the health of the optic nerve is so crucial.”
Treatments aim to slow or stop the progression of vision loss. There are three main treatments, all of which help lower pressure in the eye. The right treatment depends on several factors, including:
Glaucoma type
Severity of disease
During each treatment, a doctor regularly checks eye pressure. They also monitor the patient’s side vision and image the optic nerve. If eye pressure, side vision, or health of the optic nerve worsen, they will likely recommend additional treatment to prevent more damage.
Patients with open angle glaucoma can benefit from laser treatment to lower the eye pressure. This is the most successful initial treatment for glaucoma with open angles.
The procedure allows the eye to drain more fluid, which lowers eye pressure. According to Dr. Friedman, the procedure has been remarkably safe since its introduction in the 1970s. Beginning treatment with lasers, he adds, can lead to better outcomes than beginning treatment with eye drops.
Prescribed eye drops can reduce pressure in the eye. While many patients may only need one type of eye drop, some may need a combination of different drops. Doctors may use eye drops as an alternative for laser treatment, especially for patients with open-angle glaucoma.
Dr. Friedman recommends surgery for the most severe glaucoma cases. He also recommends surgery when glaucoma worsens and there are no other ways of effectively lowering eye pressure.